Both Ejuke and Iheanacho missed Sevilla’s 2-2 draw with Las Palmas last weekend for different reasons.
Ejuke was left out due to tactical decisions, despite his strong pre-season performances and impressive training sessions.
Pimienta reassured fans by saying: “Ejuke is doing very well. He didn’t play last time because of our decision, but he will help the team tomorrow if necessary.”
Iheanacho missed the first match due to late registration issues.
The former Leicester City man is now set to make his La Liga debut.
The duo are expected to be in action at the Ramón Sánchez Pizjuán Stadium on Friday.